[DRUG NAME] Product name: three and a rod special generic name: sarafloxacin hydrochloride soluble powder 【Properties】 light yellow powder, slightly bitter taste. Pharmacological effects Sarafloxacin is an ethyl group is replaced by a compound fluorophenyl 6-fluoroquinolone norfloxacin hydroxyl ring. Have a strong effect on resting and growing bacteria. Clinafloxacin is the fourth-generation fluoroquinolones, with broad spectrum antimicrobial, bactericidal effect, and toxic side effects and so on. Indications Cymbalta antibacterial agents for the treatment of clinically by Gram-negative bacteria and a small number of Gram-positive bacteria infections caused by disease, applicable to all types of pericarditis caused by E. coli, perihepatitis, enteritis, balloon inflammation, salpingitis, egg yolk peritonitis, arthritis, encephalitis, osteonecrosis embolism; scour caused by salmonella, typhoid, paratyphoid; at the same time on a variety of duck serositis and infections caused by Pseudomonas aeruginosa very good results. Dosage a mixed drink: chickens, ducks per 1kg of water added to the product 0.4g (per 100g watered 250kg), focus on drinking once a day. Broilers water intake by 12 hours to calculate the dosage (or press the chicken into 1 000 / bottle), 3-5 days. Prevention halved. 2, mixed feeding: chicken, duck this product per 100g spices 125kg, once a day, once every 3-5 days. Prevention halved. [Content Specification] This product contains 100g Sarafloxacin 5g. 【Packing】 100g / bottle [Storage] sealed, dry place. [Executive standard] "Chinese Veterinary Pharmacopoeia" 2005 edition a ------------------------------------- --------------- What chicken E.coli disease is? Avian colibacillosis (avian colibacillosios) is a poultry disease caused by pathogenic E. coli. Because E. coli disease often chicken and Mycoplasma disease infection, and often secondary to other diseases (such as Newcastle disease, avian influenza and confusion, infectious bronchitis, Pasteurella disease, etc.), making treatment difficult. Currently avian E. coli disease has become a major infectious disease in poultry production, often causing huge economic losses. Chicken E. coli disease symptoms? Symptoms of E. coli disease varied, are: 1. Acute lost blood chickens no significant symptoms and sudden death; or obvious symptoms; Part chickens outliers Dai Li, or crowded heap, feathers loose disorder, anorexia or waste must, yellow-white Xifen row, contaminated feathers around the anus. Higher incidence of mortality. It is currently one of the most harmful type. Commonly referred to as chicken E. coli disease refers to this type. When the diagnosis of this type depends mainly on clinical diagnosis necropsy dead chickens only to observe pathological changes made to the naked eye. 2. yolk peritonitis, also known as "egg sub plague." This is an important disease of laying hens in cages. Chickens infected with E. coli often due to tubal produce inflammation, inflammation of the product so that tubal adhesions umbrella, bell infundibulum can not open at the time of ovulation, the follicle into the fallopian tube and therefore can not fall into the abdominal cavity caused by the disease. Extensive peritonitis produce large amounts of toxins, which can cause the onset of the hens died. Many farm or breeder hens often due to the disease causing significant economic losses. Such dead, sick hen, appearance abdominal swelling, severe fall. 3. salpingitis common in laying hens. Tubal hyperemia, hemorrhage, or how the amount of internal secretions, resulting in abnormal eggs and egg containing the E. coli contaminated, severe reduction or stop laying eggs. 4. Enteritis chickens feathers beneath the anus damp, filthy, adhesions, which is a sign of the bacteria causing diarrhea. More mild symptoms of E. coli illness Click to view: Chicken Chicken E. coli disease in detail the symptoms of the disease spectrum view: Chicken E. coli symptoms of the disease prevention and control measures chicken colibacillosis map? 1. General measures are mainly environmental sanitation, strengthen management. Pay particular attention to the following aspects: Check whether the water was contaminated with E. coli, where it should be completely replaced; Note brood incubation and rearing density; birdhouse and utensils clean and disinfected regularly; breeder eggs should be set to close every day 4 eggs, dirty eggs should be wiped clean of fine sand. 2. inactivated vaccine manufacture and use of inactivated vaccine developed in laboratories abroad has long been reported, allegedly used to control the disease in the production of good results. At home, we should request production unit, made of inactivated vaccine in early 1985. Taking into account the multi-coli serotypes, which we used vaccine strains isolated from the field go back to what made the field, that the use of its own vaccine. After the majority of specialist production field and several years of large-scale use of proven, safe and reliable this inactivated vaccine, the immune effect is indeed continuous period of time that can effectively prevent and control the occurrence of this disease, even in a field, or a local regional eradication of the disease. Inactivated vaccine major manufacturing steps include: Isolation - staining - biochemical identification - pathogenicity tests - serotype identification - choose to use the system through the identification of the strain for vaccine - grade enrichment culture (final determination of the number of bacteria) - Off Live - adjuvant - security, validity check - sub-equipment use. E. coli growth curve study results showed that in nutrient broth at 37 ℃ preheated to access bacteria, can achieve growth peak after 6h. This not only provides a theoretical basis for selecting the best time for inactivation, can greatly shorten the training time and speed up the entire process of vaccine production, so that production cycles, increase production.